597562-32-8

  • Product Name:LL-37 amide trifluoroacetate salt
  • Molecular Formula:C205H341N61O52
  • Purity:99%
  • Molecular Weight:4492.27854
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Product Details;

CasNo: 597562-32-8

Molecular Formula: C205H341N61O52

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  • Molecular Formula:C205H341N61O52
  • Molecular Weight:4492.27854
  • PSA:0.00000 
  • LogP:0.00000 

LL-37 amide trifluoroacetate salt (Cas 597562-32-8) Usage

Description LL-37 amide trifluoroacetate salt is a cationic and α-helical antimicrobial peptide.

Uses

LL-37 amide trifluoroacetate salt plays an important role in the first act of defense against local infection and systemic invasion of pathogens at sites of inflammation.

597562-32-8 Relevant articles

Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity

Ziv OREN; Jeffrey C. LERMAN; Gudmundur H. GUDMUNDSSON; Birgitta AGERBERTH; Yechiel SHAI

, Biochem J (1999) 341 (3): 501–513.

The antimicrobial peptide LL-37 belongs to the cathelicidin family and is the first amphipathic α-helical peptide isolated from human. LL-37 is considered to play an important role in the first line of defence against local infection and systemic invasion of pathogens at sites of inflammation and wounds.

Degradation of Human Antimicrobial Peptide LL-37 by Staphylococcus aureus-Derived Proteinases

Magdalena Sieprawska-Lupa, Piotr Mydel, Katarzyna Krawczyk, Kinga Wójcik, Magdalena Puklo, Boguslaw Lupa, Piotr Suder

, Antimicrobial Agents and Chemotherapy Vol. 48, No. 12

In this study we examined the susceptibility of LL-37 to proteolytic degradation by two major proteinases produced by Staphylococcus aureus, a metalloproteinase (aureolysin) and a glutamylendopeptidase (V8 protease).

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